Oregon Esthetician State Board

In which layer of the epidermis are melanocytes located to produce melanin?

1. Stratum granulosum

2. Stratum spinosum

3. Stratum lucidum

4. Stratum germinativum

The correct answer is: Stratum germinativum

Melanocytes, which are responsible for the production of melanin, are located in the stratum germinativum, also known as the basal layer of the epidermis. This layer is the deepest part of the epidermis and is where new skin cells are generated. Melanocytes reside among the keratinocytes in this layer and extend their dendritic processes to distribute melanin to nearby cells, which helps to protect the skin from harmful UV radiation and contributes to skin pigmentation. The other layers mentioned are not where melanocytes are found. The stratum granulosum is primarily involved in the process of keratinization, where keratinocytes begin to die and form a waterproof barrier. The stratum spinosum is the layer above the stratum germinativum, where cells start to flatten out and may contain cells related to immune response but not melanocytes. The stratum lucidum is a thin, clear layer found only in certain areas of thick skin (like palms and soles) and does not contain melanocytes either. Understanding the specific roles and locations of different skin cells is essential for estheticians when dealing with skin care and treatment protocols.